Heme oxygenase-1 induction contributes to renoprotection by G-CSF during rhabdomyolysis-associated acute kidney injury
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منابع مشابه
Heme oxygenase-1 induction contributes to renoprotection by G-CSF during rhabdomyolysis-associated acute kidney injury.
Granulocyte colony-stimulating factor (G-CSF) is renoprotective during acute kidney injury (AKI) induced by ischemia and cisplatin nephrotoxicity; however, the underlying mechanism is not entirely clear. Rhabdomyolysis is another important clinical cause of AKI, due to the release of nephrotoxins (e.g., heme) from disrupted muscles. The current study has determined the effects of G-CSF on rhabd...
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Purpose: Effect of lipocalin 2 on the expression of heme oxygenase I , II and NF-kB transcription factor was the purpose of this survey. Materials and Methods: Lcn2 was cloned to pcDNA3.1 plasmid by using genetic engineering method. The recombinant vector was transfected to CHO and HEK293T to establish stable cell expressing lipocalin 2. The presence of lipocalin 2 gene in these cells was confi...
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Proximal tubule-targeted heme oxygenase-1 in cisplatin-induced acute kidney injury 1 2 3 4 Subhashini Bolisetty, Amie Traylor, Reny Joseph, Abolfazl Zarjou, Anupam 5 Agarwal 6 7 Department of Medicine, Nephrology Research and Training Center and Department of Cell, 8 Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, 9 Alabama 35294, Birmingham Veterans Admi...
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From the Muscle Research Unit, Depart ment of Internal Medicine (X.B., J.M.G.), and the Department of Nephrology (E.P.), Hospital Clínic, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Univer sity of Barcelona, Barcelona. Address re print requests to Dr. Grau at the Muscle Research Unit, Department of Internal Medicine, Hospital Clínic, Institut d’Inves tigacions Biomèdiques Augu...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Renal Physiology
سال: 2011
ISSN: 1931-857X,1522-1466
DOI: 10.1152/ajprenal.00438.2010